Celebrex side effects Get emergency medical help if you have signs of an allergic reaction to Celebrex ( hives , difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat , burning eyes, skin pain, red or purple skin rash with blistering and peeling). WARNING: RISK OF SERIOUS CARDIOVASCULAR AND GASTROINTESTINAL EVENTS. Cardiovascular Thrombotic Events. Nonsteroidal anti-inflammatory drugs (NSAIDs) cause an increased risk of serious cardiovascular thrombotic events, including myocardial infarction, and stroke, which can be fatal. Find patient medical information for Celebrex Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. WARNING. RISK OF SERIOUS CARDIOVASCULAR AND GASTROINTESTINAL EVENTS. Cardiovascular Thrombotic Events. Nonsteroidal anti-inflammatory drugs (NSAIDs) cause an increased risk of serious cardiovascular thrombotic events, including myocardial infarction, and stroke, which can be fatal. … sleep has been associated with increased risk of adverse cardiovascular outcomes,… hypnotic with increasingly recognized variability in metabolism and next-morning drug levels and side effects, particularly in women and older adults. BOSTON , MA — By the beginning of this year, a consensus had developed on the link between COX-2 drugs and heart disease risk: The evidence for cardiovascular side effects was strongest for Vioxx and Bextra, intermediate for Celebrex, and weak for naproxen. Celebrex was even safer when it came to certain side effects, like serious gastrointestinal problems. The results surprised Nissen and other heart experts involved in the study, he said. People taking 200 mg of Celebrex twice a day more than doubled their risk of dying of cardiovascular disease. Those on 400 mg twice a day more than tripled their risk, compared with people taking a placebo. SIDE EFFECTS. The following adverse reactions are discussed in greater detail in other sections of the labeling: Cardiovascular Thrombotic Events [see WARNINGS AND PRECAUTIONS] Find information about common, infrequent and rare side effects of Celebrex Oral.